I personally use a i-tec USB 3.0 Hub. All my Polyend Gear (Tracker / Tracker+ / Mini / Play / Play+) runs through it. I’ve used MIDI and Audio successfully. It does not come with a USB-C cable, but you can easily replace it with a USB-C ↔ USB3.0 B cable.
In my case i actually have to run it with a powered hub, else the devices don’t show up at all (seems to be a AMD chipset specific issue). I know this is about Mac devices, but i’ve ran them with the same hub from a M1 Macbook Air as well before.
So in general i think they do work with hubs, but i understand that Polyend does not officially support it. As it adds a ton of complexity, when something doesn’t work the way it should, because an unknown variable/hardware device was introduced in the chain.
TLDR: From my own experience - it works, but if you run into any issues, you are on your own (unless someone here can help you 
).